isphosphonates are drugs that are used to help strengthen and reduce the risk of fractures in bones that have been weakened by metastatic breast cancer. Examples include pamidronate (Aredia) and zoledronic acid (Zometa). They are given intravenously (IV).
Bisphosphonates may also help against bone thinning (osteoporosis) that can result from treatment with aromatase inhibitors (see above) or from early menopause as a side effect of chemotherapy. There are a number of medicines, including some oral forms of bisphosphonates, to treat the loss of bone strength that is not caused by breast cancer in the bone.
Bisphosphonates can have side effects, including flu-like symptoms and bone pain. A rare but very distressing side effect of intravenous bisphosphonates is damage (osteonecrosis) in the jaw bones.
post by santan.., 21st.., july......
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